Spongebob
The resilience of Spongebob operates on both physical and psychological planes. His porous biology absorbs damage that would destroy conventional organisms, regenerating from states constituting permanent death. He has been dried, frozen, and flattened, returning each time with undiminished enthusiasm.
Psychologically, having failed his driving examination 1,258,056 times, he approaches each attempt renewed. No failure produces despair. This is resilience as metaphysical principle.
Thanos
The Mad Titan demonstrates considerable resilience, having endured millennia of existence, numerous assassination attempts, and the universal rejection of his philosophy. His commitment to his cause never wavered despite opposition from the galaxy's most powerful defenders.
However, his resilience proved finite. Defeat by the Avengers ultimately broke his conviction, leading him to destroy the Infinity Stones and await death. The Titan could endure anything except being wrong.